%0 Journal Article %T Hybrid Catalysis: A Suitable Concept for the Valorization of Biosourced Saccharides to Value-Added Chemicals %+ Institut Charles Viollette (ICV) - EA 7394 (ICV) %+ IFP Energies nouvelles (IFPEN) %+ Unité de Catalyse et Chimie du Solide - UMR 8181 (UCCS) %A Gimbernat, Alexandra %A Guehl, Marie %A Capron, Mickaël %A Froidevaux, Renato %A Girardon, Jean-Sébastien %A Dhulster, Pascal %A Delcroix, Damien %A Dumeignil, Franck %A Lopes Ferreira, Nicolas %< avec comité de lecture %@ 1867-3899 %J ChemCatChem %I Wiley %V 9 %N 12 %P 2080 - 2084 %8 2017-06-22 %D 2017 %R 10.1002/cctc.201601633 %K Biocatalysis %K Biomass %K Carbohydrates %K Hybrid catalysts %Z Chemical Sciences %Z Chemical Sciences/CatalysisJournal articles %X Through biomass valorization, sugars can become a majorcarbon resource for the production of fuels and chemicals byusing catalysis. Hybrid catalysis, a direct combination of biocatalysisand chemocatalysis, may yield innovative solutions. 5-Hydroxymethylfurfural (5-HMF) is a platform molecule derivedfrom glucose, for which fructose is a key intermediate. To overcomethe thermodynamic enzymatic equilibrium between glucoseand fructose, two methodologies based on hybridcatalysis are described herein. In the first method, the glucoseisomerase and fructose-to-5-HMF dehydration chemocatalystsare simultaneously implemented in a multiphasic way to implythe complexation and transport of fructose. The secondmethod proposes a route through sorbitol, obtained by thehydrogenation of glucose. Sorbitol is then enzymatically convertedinto fructose, whereas regeneration of the cofactor isperformed in situ with an organometallic complex as achemocatalyst. %G English %L hal-01582182 %U https://ifp.hal.science/hal-01582182 %~ UNIV-ARTOIS %~ IFP %~ CNRS %~ UNIV-LITTORAL %~ INRA %~ UCCS %~ INC-CNRS %~ AGREENIUM %~ UNIV-LILLE %~ INRAE %~ TEST-HALCNRS %~ TEST2-HALCNRS